Basic PRK / LASEK
Including initial consultation and laser eye surgery.
Laser eye surgery: which method is best for you? Get all key information here.
More and more people have their eyes lasered to become independent from glasses or contact lenses. But which form of laser eye surgery is best for you personally: Trans-PRK, LASIK, Femto-LASIK or ReLEx SMILE or Laser Blended Vision? What should you look out for before you decide on a laser eye surgery method or a surgeon? Here, we will describe all forms of laser eye surgery which are used to correct myopia, hyperopia, astigmatism or presbyopia. We take a closer look at various criteria so that you can compare yourself:
The terms laser eye surgery and LASIK are often used synonymously. In fact, however, LASIK is only one of three generations in the development of laser eye surgery. Each innovation intended to reduce the risks and side effects of a laser eye surgery technique. Due to the higher safety and absence of pain, we recommend our patients having their eyes lasered using ReLEx SMILE, the most advanced method, whenever possible. Only if this is not possible do we consider other laser techniques. We will help you select the safest and most effective method to have your eyes lasered. When selecting your surgeon, you should therefore check whether they offer all techniques. This is the only way to ensure that they will choose the ideal method for you.
Since 2013, our senior surgeon Dr. Detlev Breyer has been a Focus magazine top medical practitioner for “No more glasses laser eye surgery”, presbyopia and cataract. He has already performed over 45,000 surgical procedures himself. As one of the first 10 surgeons in the world to use ReLEx SMILE, the gentle flapless laser eye surgery technique, he has made a name for himself in lens and cataract surgery by playing a leading role in the development of microincision surgery and multifocal lens surgery.
His experience in laser eye surgery as well as cataract surgery provide you with additional security.
“At Premium Eyes, your eyes will be lasered exclusively and personally by me in a hygiene-certified surgical suit for intraocular procedures.”
Focus Top Medical Practitioner Dr. Detlev Breyer
Our Refractive Manager is happy to answer your questions.
ReLEx SMILE is the first method which does not require a corneal flap. It was developed in cooperation with the company Carl Zeiss Meditec and introduced for the first time in 2007. In contrast to earlier laser eye surgery methods, only a femtosecond laser is used, the VISUMAX by Zeiss. What makes ReLEx SMILE special is that the correction of the visual impairment is done inside the cornea. The femtosecond laser cleaves a lenticule in the cornea which is then extracted carefully by the surgeon through a 2 mm opening under the surgery microscope in the next step. If you decide to have your eyes lasered with ReLEx SMILE, you should choose an experienced surgeon since the surgeon’s experience plays a significantly larger role for this laser eye surgery method than for other laser techniques. But it is safer, does not cause dry eyes and is therefore ideally suited if you suffer from contact lens intolerance.
The most important advantages are the intraoperative and long-term safety and freedom of pain. The top corneal layer remains intact and the eyes stable during the laser treatment. Only one small step is required to remove the lenticule. Significantly less corneal nerves are severed compared to a method requiring a flap such as LASIK or Femto-LASIK. Flap-related risks and side effects are eliminated.
Our area of application:
With the introduction of the femtosecond laser into refractive surgery, Femto-LASIK was performed for the first time in 2004. The term Femto-LASIK is slightly misleading since the actual correction of the cornea is performed using the excimer laser with this laser eye surgery method as well. The femtosecond laser merely prepares the flap, i. e. the corneal lid. The advantage is that a blade is no longer required and that laser eye surgery using Femto-LASIK is slightly safer that LASIK using the microkeratome. Miscuts can be corrected since the femtosecond laser does not produce smooth cuts but leaves gas bubbles in the tissue with tissue bridges in-between. If these are not severed, the bubbles dissolve and the tissue is as stable as before. Using Femto-LASIK, vision impairments can be corrected more accurately than with LASIK. Wavefront-guided methods are mainly suitable for the correction of an unfavorable laser result. Wavefront-optimized methods, however, are also suitable for the first surgery.
Flap-related risks The corneal flap will never grow attached as tightly as before after the surgery. The cutting surface is only held by adhesion. Scars will only form at the cut edges. This is why the flap can still be lifted off after years, e. g. for another LASIK. It can detach anytime due to external impacts, e. g. sports injuries, pets or accidents. It is a known fact that the scars which form at the edges are more stable with Femto-LASIK than with LASIK.
Learn more about Femto-LASIK.
All LASIK methods cause a dry eye for 3 to 6 months. A dry eye is the most common reason for contact lens intolerance. This is only one of the reasons why with an existing contact lens intolerance, the ReLEx SMILE method should be favored over Femto-LASIK. If contact lenses have to be worn again later in life, e. g. due to presbyopia, this is safely possible thanks to the stability after ReLEx-SMILE surgery.
Area of application:
Limit area:
If you would like to have your eyes lasered and become independent of glasses or contact lenses, please make an appointment for a non-binding initial consultation or preliminary assessment with your eye laser specialist Dr. Breyer via phone or email. We will also be happy to call you back. We are looking forward to hearing from you.
The first laser eye surgery performed on humans was photorefractive keratectomy (PRK) using the excimer laser. It was performed for the first time in 1987 and is therefore considered as the first generation of laser eye surgery. With this laser technique, the corneal epithelium is removed mechanically beforehand either using a scalpel, alcohol, a microkeratome or a laser. Then, the top corneal layer underneath is reshaped using an excimer laser. After the laser procedure, a bandage must be worn for several days until the epithelium has regenerated.
The largest drawback is the safety profile: In comparison to the laser techniques that followed, all PRK methods have three things in common: postoperative pain for approx. 4 days, an increased risk of infection and slow vision recovery over 4-6 weeks. For these reasons, we recommend our patients only in exceptional cases having their eyes lasered using these obsolete methods.
With laser eye surgery using LASEK (laser-assisted sub-epithelial keratectomy), the epithelium is pre-treated with alcohol, detached manually using special instruments, lifted off and folded away. After the laser surgery, the epithelium is repositioned. The pre-treatment of the epithelium with alcohol can impair healing. A bandage contact lens must be worn for 1 to 3 days, the pain is somewhat less than with PRK and visual acuity is supposed to return quicker.
Laser eye surgery using Epi-LASIK (epithelial LASIK) is another advanced variant of PRK which involves less risks than LASIK. With this laser eye surgery technique as well, the entire epithelial sheet is lifted off and folded away to be returned to its original position after the surgery. However, in this case, a similar microkeratome is used as for LASIK. This means that there are no alcohol-related healing impairments as with LASEK but there is a risk of miscuts. In this case as well, visual acuity is supposed to return more quickly.
The higher risk is due to the cut using the microkeratome. With Epi-LASIK, the epithelial sheet is cut using a microkeratome. This means that there is a risk of a miscut which cannot be corrected anymore. We therefore do not recommend Epi-LASIK.
Learn more about PRK, LASEK and epi-LASIK.
With Trans-PRK (transepithelial photorefractive keratectomy), the preparation of the epithelial sheet is usually performed directly together with the ablation to correct the quality of vision using an excimer laser. Essentially the same but in a ‘fancier dress’.
Area of application of all PRK methods :
Limit area of all PRK methods :
Since an excimer laser could only be used at the surface of the cornea but the removal of the surface as it was required for PRK causes significant pain and risks, research was conducted into a new method. The idea: removing the top corneal layer underneath the pain-sensitive epithelium of the cornea leaving only a small bridge and folding it to one side like a lid. Then, the MEL 60 was used, a predecessor of the now popular ophthalmological excimer laser, to remove the cornea in the deeper stroma and to correct the impaired vision in this way. This new laser eye surgery technique was called laser-assisted in situ keratomileusis, reshaping of the inner cornea using laser (from ancient Greek Κερατων cornea; Μιλευσισ shaping), LASIK in short. It was first performed in 1989 by Prof. I. Pallikaris at the University of Crete in Greece. This laser eye surgery technique has a relatively flat learning curve for ophthalmologists and is therefore also offered by ophthalmologists who rarely or never perform any other eye surgeries. This could be a disadvantage for the patient if complications occur.
Several million LASIK treatments have already been performed. 90% of the patients are satisfied with the result, 10% suffer from side effects of the flap.
Cutting the flap using the microkeratome. With LASIK the corneal flap is cut using a microkeratome. This means that there is a risk of a miscut which can only be corrected 4 weeks later.
Other flap-related risks The corneal flap will not grow attached as before. The cutting surface is held by adhesion. Scars will form at the cut edges. This is why the flap can still be lifted off after years, e. g. for another LASIK. It can detach anytime due to external impacts, e. g. sports injuries, pets or accidents.
All LASIK methods cause a dry eye for 3 to 6 months. A dry eye is the most common reason for contact lens intolerance. This is only one of the reasons why with an existing contact lens intolerance, the ReLEx SMILE method should be favored over LASIK or Femto-LASIK. Even if contact lenses have to be worn again later in life, e. g. due to presbyopia, this is safely possible thanks to the stability after a ReLEx-SMILE surgery.
Area of application:
Limit area:
No surgery is free of risks. This also applies to laser eye surgery. Even if the infection rate of an inflammation of the cornea which is caused by microbes (microbial keratitis) is lower than if contact lenses are worn for 5 years, there is still a small residual risk. Please make an appointment with us. We will inform you in detail and without time constraints.
Presbyopia is different from myopia, hyperopia or astigmatism due to its cause: Over the course of our life, the lens of the eye becomes less flexible and can no longer correctly adjust (accommodate) the refraction of the eye to the closeness of an object. This happens approximately in our mid-40s. At this age, most people become more and more hyperopic. Since the flexibility of the eye lens cannot be restored, there are two state-of-the-art laser eye surgery methods to help you stay independent of reading or varifocal glasses: Monovision or blended vision using Presbyond laser eye surgery.
For laser eye surgery to correct vision impairments at the cornea, two types of lasers are usually used: excimer lasers and femtosecond lasers.
Function: Excimer lasers are gas lasers which can generate electromagnetic radiation in the ultraviolet wavelength range. State-of-the-art models include e. g. MEL 80 by Zeiss which generates radiation with a wavelength of 193 nm at a frequency of 250 Hz or the successor MEL 90 with a frequency of 250 to 500 Hz. If tissue is removed using an excimer laser, the tissue is evaporated by the laser spot. The smaller the spot, the more precise the removal. The spot size of MEL 80 and MEL 90 is 0.7 mm. The tissue around the laser spot is heated up only slightly. Since unpleasant vapors and odors develop during the laser procedure – similar to burning skin or hair – excimer lasers usually have an integrated smoke vent.
Area of application: The excimer laser is used to remove tissue in PRK, LASEK, Epi-LASIK, LASIK and Femto-LASIK. If it is supposed to remove tissue inside the cornea, the tissue above has to be removed or folded away first. With PRK, LASEK and Epi-LASIK, the epithelium of the cornea is removed in different ways. With LASIK and Femto-LASIK, a flap is cut and folded to the side.
Effectiveness: Tissue ablation using an excimer laser can be very precise based on an exact preliminary examination. Using wavefront-guided ablation profiles is also possible. They compensate for minor deviations of the corneal surface from an optimum sphere to achieve an even better quality of vision.
Patient interface: In the area where the patient comes into contact with the patient, there is a so-called contact glass. At the moment, excimer lasers have a contact glass which is attached to the patient’s eye using a considerably high suction and flattens it. This flattening temporarily increases the pressure in the eye. Usually, the patient only sees black at this moment – this is called “blackout” of the eye.
Safety: A cut with an excimer laser cannot be undone since corneal tissue does not regenerate once it is evaporated. To prevent miscuts and increase safety during laser eye surgery, state-of-the-art excimer lasers have an Eyetracking system which precisely tracks the patient’s eye movements. Within a certain tolerance range, minor movements can be compensated during ablation. If the patient moves the eye too much, the laser procedure is interrupted or stopped.
Function: Femtosecond lasers send light pulses with a duration in the femtosecond range. One femtosecond (fs) equals 10-15 seconds. In contrast to an excimer laser, a femtosecond laser can send its laser pulses also to an exactly calculated tissue depth. The tissue above does not have to be removed. One of the most advanced models for use in refractive cornea surgery is the VisuMax femtosecond laser by the company Zeiss. It generates radiation with a wavelength of 1043 nm. The pulse duration is 220 to 580 fs with a laser pulse rate of 500 kHz. A femtosecond laser does not generate any heat by tiny gas bubbles inside the tissue. For a cut, many tiny gas bubbles are generated next to each other with small tissue bridges in-between. Only if the surgeon removes these bridges is the cut performed and the tissue severed. No unpleasant odors or noises occur.
Area of application: A femtosecond laser is used for example to cut the flap during Femto-LASIK. This is the decisive difference between the methods: With LASIK, the flap is cut using the microkeratome, with Femto-LASIK using the femtosecond laser. In addition, VisuMax is the only lasers which can be used to perform the ReLEx SMILE laser eye surgery. For this procedure, the VisuMax creates a precisely calculated cornea disc (lenticule) inside the cornea. When it is removed through a tiny opening, the defective vision of the eye is corrected. Among other things, cornea cuts and the preparation of a fine tunnel in the cornea to insert annular segments to stabilize the cornea can be performed using the VisuMax.
Effectiveness: Femtosecond lasers have been used for laser eye surgery since 2004. Initially as a replacement for the microkeratome, since thinner flaps can be cut using the femtosecond laser than using the microkeratome. The VisuMax femtosecond laser is as good as the excimer laser in terms of precision and effectiveness. This has meanwhile been confirmed in numerous studies. Since the introduction of the ReLEx SMILE procedure at the latest, it is also known that the VisuMax can be used to create the same exact ablation or cutting profiles as an excimer laser and that it allows for a precise correction of the defective vision based on an exact preliminary examination, even wavefront-optimized ablation profiles.
Patient interface: A huge advantage of the VisuMax is its anatomically shaped contact glass. It applies significantly less pressure to the eye since it is adapted to the spherical shape of the eye. This means that there is no blackout of the eye.
Safety: If a surface has been prepared using a femtosecond laser, only gas bubbles form at first. Only when the tissue bridges between them are severed is there an actual cut. If a mistake has happened, the simple solution is to wait until the gas bubbles have been absorbed. Approx. 4 weeks later, the laser procedure can be repeated as if nothing had happened. This means that miscuts are not possible if a femtosecond laser is used which increases the safety significantly in particular in comparison to a flap cut using a microkeratome.
"The bitterness of poor quality remains long after the sweetness of low price is forgotten."
Including initial consultation and laser eye surgery.
Including initial consultation, preliminary examination, laser eye surgery, and follow-up examination.
Including initial consultation and laser eye surgery.
Including initial consultation, preliminary examination, laser eye surgery, and follow-up examination.
Including initial consultation, preliminary examination, laser eye surgery, and follow-up examination for higher prescriptions (3 dpt and astigmatism).
Including initial consultation, preliminary examination, laser eye surgery, and three follow-up examinations.
Including initial consultation, preliminary examination, laser eye surgery, and three follow-up examinations.
Including initial consultation, preliminary examination, laser eye surgery, and one follow-up examination performed on a weekend. Two additional follow-up examination will be one week after surgery and one month after surgery – if you wish to both could be scheduled on weekends too.
Including initial consultation, preliminary examination, laser eye surgery, and three follow-up examinations.
Including initial consultation, preliminary examination, laser eye surgery, and three follow-up examinations.
If you would like to have your eyes lasered and become independent of glasses or contact lenses, please make an appointment for a non-binding initial consultation or preliminary assessment with your eye laser specialist Dr. Breyer via phone, email or our appointment scheduling app. We will be happy to call you back. We are looking forward to hearing from you.
Masters J, Kocak M, Waite A, in: J Cataract Refract Surg. 2017 Jan;43(1):67-73. PMID: 28317680
DOI: 10.1016/j.jcrs.2016.10.022
Breyer D.R.H., Kaymak H., Klabe K., Ax T., Hagen P.R., in: Tägliche Praxis 60, 637–651 (2018)